Phenotypes associated with this allele

• Allele Symbol: Grhl3^ct-J
• Allele Name: curly tail Jackson
• Allele ID: MGI:1860481
• Summary: 3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Grhl3^ct-J/Grhl3^ct-J	STOCK T(7;15)9H	MGI:2687296
ht2	Grhl3^ct/Grhl3^ct-J	Not Specified	MGI:2687310
cx3	Grhl3^ct-J/Grhl3^ct-J mct1^C57BL/6J/mct1^C57BL/6J	involves: BALB/cByJ * STOCK ct/J	MGI:3612268

Genotype
MGI:2687296

hm1

• Allelic Composition: Grhl3^ct-J/Grhl3^ct-J
• Genetic Background: STOCK T(7;15)9H

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

limbs/digits/tail

curly tail ( J:87487 )

• the incidence of curly tails and/or spina bifida in liveborn mice of this stock is ~12.5%

nervous system

open neural tube ( J:87487 )

• in addition to the kinked tails, some mice had spina bifida

• the incidence of curly tails and/or spina bifida in liveborn mice of this stock is ~12.5%

embryo

open neural tube ( J:87487 )

• in addition to the kinked tails, some mice had spina bifida

• the incidence of curly tails and/or spina bifida in liveborn mice of this stock is ~12.5%

Genotype
MGI:2687310

ht2

• Allelic Composition: Grhl3^ct/Grhl3^ct-J
• Genetic Background: Not Specified

limbs/digits/tail

curly tail ( J:87487 )

• crosses between ct^J homozygotes and mice of the homozygous STOCK ct/J line, within which 30-50% of mice are affected, yielded only ~7.4% affected offspring; the reduced penetrance of the phenotype in the presumed complex heterozygote may be due either to the combination of the two ct alleles or to a "hybrid vigor" effect of combining the by-now inbred genetic backgrounds

nervous system

open neural tube ( J:87487 )

embryo

open neural tube ( J:87487 )

Genotype
MGI:3612268

cx3

• Allelic Composition: Grhl3^ct-J/Grhl3^ct-J; mct1^C57BL/6J/mct1^C57BL/6J
• Genetic Background: involves: BALB/cByJ * STOCK ct/J

limbs/digits/tail

curly tail ( J:29366 )