Phenotypes associated with this allele
Allelic Composition |
Wc/Wc
|
|
Genetic Background |
Not Specified |
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Wc mutation
(1 available);
any
Wc mutation
(1 available)
|
|
|
mortality/aging
|
• all homozygotes die before birth
|
embryo
|
• subsequent to embryoblast differentiation into embryonic and extra-embryonic ectoderm, the embryonic ectoderm becomes pyknotic and degenerates, although the yolk sac, chorion, and allantois are normal
|
Allelic Composition |
Wc/Wc+
|
|
Genetic Background |
Not Specified |
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Wc mutation
(1 available);
any
Wc mutation
(1 available)
|
|
|
pigmentation
|
• lighter coat color by 4 to 5 days of age
|
integument
|
• heterozygotes have a wavy, diluted coat, with fuzzy hair on the head and upper back by 4 to 5 days of age
|
|
• lighter coat color by 4 to 5 days of age
|
|
• wavy, irregular vibrissae by 4 to 5 days of age
|
|
• the more severely affected heterozygotes have dry, scaly skin shortly after birth and no hair develops, followed by death before weaning
|