Phenotypes associated with this allele

• Allele Symbol: Oca2^p-12DTR
• Allele Name: pink-eyed dilution 12DTR
• Allele ID: MGI:1857920
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Oca2^p-12DTR/Oca2^p-12DTR	involves: 101/Rl * C3H/Rl	MGI:3826391
ht2	Oca2^p-12DTR/Oca2^p	Not Specified	MGI:3826442

Genotype
MGI:3826391

hm1

• Allelic Composition: Oca2^p-12DTR/Oca2^p-12DTR
• Genetic Background: involves: 101/Rl * C3H/Rl

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:29903 )

preweaning lethality, complete penetrance ( J:29903 )

• mortality at various preweaning ages

pigmentation

diluted coat color ( J:29903 )

• coat color is darker than classical pink-eyed dilution coat pigmentation

behavior/neurological

abnormal involuntary movement ( J:29903 )

• when picked up mice exhibit twitching of hindlimbs

tremors ( J:29903 )

• tremor of forelimbs follows twitching of hindlimbs when mice are picked up

growth/size/body

decreased body size ( J:29903 )

• compared to like-sexed wild-type littermates

reproductive system

female infertility ( J:29903 )

♀

male infertility ( J:29903 )

♂

integument

diluted coat color ( J:29903 )

• coat color is darker than classical pink-eyed dilution coat pigmentation

Genotype
MGI:3826442

ht2

• Allelic Composition: Oca2^p-12DTR/Oca2^p
• Genetic Background: Not Specified

pigmentation

diluted coat color ( J:29903 )

• coat color (eumelanin pigment) is intermediate between the coat color of Oca2^p/Oca2^p and wild-type mice

decreased eye pigmentation ( J:29903 )

• eyes of newborns are not fully pigmented and darken with age

vision/eye

decreased eye pigmentation ( J:29903 )

• eyes of newborns are not fully pigmented and darken with age

integument

diluted coat color ( J:29903 )

• coat color (eumelanin pigment) is intermediate between the coat color of Oca2^p/Oca2^p and wild-type mice