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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Oas1bFlv-r
flavivirus resistance
MGI:1857800
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Oas1bFlv-r/Oas1bFlv-r C3.PRI-Oas1bFlv-r MGI:5285417
hm2
 		Oas1bFlv-r/Oas1bFlv-r multiple strains MGI:2429410


Genotype
MGI:5285417
hm1
Allelic
Composition		 Oas1bFlv-r/Oas1bFlv-r
Genetic
Background		 C3.PRI-Oas1bFlv-r
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oas1bFlv-r mutation (2 available); any Oas1b mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased susceptibility to Flaviviridae infection ( J:175365 )
• mice infected with 17D yellow fever virus do not develop disease symptoms unlike C3H/He mice




Genotype
MGI:2429410
hm2
Allelic
Composition		 Oas1bFlv-r/Oas1bFlv-r
Genetic
Background		 multiple strains
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oas1bFlv-r mutation (2 available); any Oas1b mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased susceptibility to Flaviviridae infection ( J:15009 )
• viral replication was inhibited in mice from resistant strains upon innoculation with the following viruses: Yellow Fever, Dengue Fever, West Nile Fever, Japanese Encephalitis, St. Louis Encephalitis, Russian Spring Summer Encephalities




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory