Phenotypes associated with this allele

• Allele Symbol: Hoxc4⁺
• Allele Name: wild type
• Allele ID: MGI:1857571
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Hoxc4^tm1Hsu/Hoxc4^+	involves: 129S/SvEv * A/J	MGI:3796845
ht2	Hoxc4^tm1Mrc/Hoxc4^+	involves: 129S7/SvEvBrd * C57BL/6	MGI:3844584

Genotype
MGI:3796845

ht1

• Allelic Composition: Hoxc4^tm1Hsu/Hoxc4⁺
• Genetic Background: involves: 129S/SvEv * A/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skeleton

xiphoid process foramen ( J:31635 )

• in some mutants, xiphoid process is observed to have an aperture or fissure

abnormal rib development ( J:31635 )

• some newborns exhibit formation of rib heads on cervical vertebra C7 compared to no wild-type animals; ossified processes extending toward the midline are seen on the ventral side of C7

abnormal thoracic vertebrae morphology ( J:31635 )

• in very small number of mutants

Genotype
MGI:3844584

ht2

• Allelic Composition: Hoxc4^tm1Mrc/Hoxc4⁺
• Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

skeleton

abnormal sternocostal joint morphology ( J:34198 )

• unlike in wild-type mice, the eighth pair of ribs in 8% of mice is attached to the sternum

abnormal thoracic vertebrae morphology ( J:34198 )

• in 3 of 35 mouse the dorsal processes of T2 and T3 are the same size unlike in wild-type mice

• occasionally the transitional vertebra is T11 instead of T10 in wild-type mice

thoracic vertebral transformation ( J:34198 )

• 4 of 6 mice exhibit a T10 transformed into T9 and weak transformations of T11 in 50% of mice