Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Agtpbp1pcd-3J mutation
(2 available);
any
Agtpbp1 mutation
(66 available)
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hematopoietic system
N |
• mice exhibit normal red blood cell, white blood cells and platelet counts, platelet morphology and spleen size
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behavior/neurological
N |
• no obvious phenotypes in neural degeneration or motor skill disorders
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homeostasis/metabolism
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Agtpbp1pcd-3J mutation
(2 available);
any
Agtpbp1 mutation
(66 available)
|
|
|
behavior/neurological
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• age of onset 3 - 4 weeks
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cellular
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• abnormally shaped sperm
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immune system
N |
• mice exhibit normal response to herpes simplex virus (HSV) and vaccinia virus (VACV) infection
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reproductive system
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• abnormally shaped sperm
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vision/eye
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• photoreceptor cell degeneration, age of onset, 18 - 25 days
• complete degeneration over the course of 1 year
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nervous system
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• thalamic neuronal degeneration, age of onset 50 - 60 days
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• mitral cells of olfactory bulb degenerate slowly and progressivley
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• partial granule cell degeneration following Purkinje cell degeneration
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• photoreceptor cell degeneration, age of onset, 18 - 25 days
• complete degeneration over the course of 1 year
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