Analysis Tools
craniofacial
|
• formation of vesicles is frequent on the ventral surface of the tongue
|
digestive/alimentary system
|
• formation of vesicles is frequent on the ventral surface of the tongue
|
integument
|
• large patches of hair loss over most of body at 15-18 days of age
• at 2 weeks of age, during the second hair cycle, appearance of fur is normal
• alopecia reappears around 8 weeks
|
|
• hair easily plucked from follicles at 15-18 days of age
|
sparse hair
(
J:42792
)
|
• hair loss evident prior to weaning
• hair loss very severe
|
|
• hair fibers become dystrophic and disintegrate in catagen and telogen
|
|
• separation of the inner and outer root sheaths of anagen follicles
• layer separation as early as 3 weeks in anagen hair follicles near sebaceous glands
|
|
• stratum granulosum is thin
|
blistering
(
J:42792
)
|
• vesicles form on the foot pads and, rarely, the interfollicular epidermis
• frequently observed at the mucocutaneous junction of the eyelid and on the muzzle, particularly when exposed to a strong air flow
• separation between basal and suprabasilar cells
|
growth/size/body
|
• formation of vesicles is frequent on the ventral surface of the tongue
|
Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
| pemphigus vulgaris | DOID:0060851 |
OMIM:169610 |
J:46865 | |
