All Phenotypes Ednrb<s-15DttMb> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ednrb^s-15DttMb
irradiation induced 15DttMb
MGI:1857328

Summary

5 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ednrb^s-15DttMb/Ednrb^s-15DttMb	involves: 101/Rl * C3H/Rl	MGI:3760667
hm2	Ednrb^s-15DttMb/Ednrb^s-15DttMb	involves: 101/Rl * C3H/Rl * C57BL/6J	MGI:3760669
ht3	Ednrb^s-15DttMb/Ednrb⁺	involves: 101/Rl * C3H/Rl	MGI:3850210
ht4	Ednrb^s-15DttMb/Ednrb^s	involves: 101/Rl * C3H/Rl	MGI:3850211
cx5	Ednrb^s-15DttMb/Ednrb⁺ Mycbp2^tm1.1Adia/Mycbp2⁺	involves: 101/Rl * C3H/Rl * C57BL/6 * FVB/N	MGI:3760666

Allelic Composition	Ednrb^s-15DttMb/Ednrb^s-15DttMb
Genetic Background	involves: 101/Rl * C3H/Rl

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ednrb^s-15DttMb mutation (0 available); any Ednrb mutation (103 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

neonatal lethality, complete penetrance ( J:16291 , J:100221 )

• die shortly after birth (J:100221)

nervous system

abnormal nervous system morphology ( J:100221 , J:125702 )

• CNS abnormalities (J:100221)

• authors state that mice exhibit the same gross morphological defects as observed in Phr1^tm1.1Adia homozygotes (J:125702)

abnormal brain morphology ( J:125702 )

• mice exhibit a general reduction in neurofilaments in the cortex, hippocampal formations including the dentate gyrus, and in the thalamus

skeleton

abnormal skeleton morphology ( J:100221 )

• skeletal abnormalities and transformation

Allelic Composition	Ednrb^s-15DttMb/Ednrb^s-15DttMb
Genetic Background	involves: 101/Rl * C3H/Rl * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ednrb^s-15DttMb mutation (0 available); any Ednrb mutation (103 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal phrenic nerve morphology ( J:87686 )

• motor neuron innervation of the diaphragm is incomplete

muscle

abnormal diaphragm morphology ( J:87686 )

• motor neuron innervation of the diaphragm is incomplete

Allelic Composition	Ednrb^s-15DttMb/Ednrb⁺
Genetic Background	involves: 101/Rl * C3H/Rl

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ednrb^s-15DttMb mutation (0 available); any Ednrb mutation (103 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

growth/size/body

decreased body size ( J:100221 )

• described as small, runted

Allelic Composition	Ednrb^s-15DttMb/Ednrb^s
Genetic Background	involves: 101/Rl * C3H/Rl

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ednrb^s mutation (19 available); any Ednrb mutation (103 available)
Ednrb^s-15DttMb mutation (0 available); any Ednrb mutation (103 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

white spotting ( J:100221 )

growth/size/body

decreased body size ( J:100221 )

• described as small, runted

integument

white spotting ( J:100221 )

Allelic Composition	Ednrb^s-15DttMb/Ednrb⁺ Mycbp2^tm1.1Adia/Mycbp2⁺
Genetic Background	involves: 101/Rl * C3H/Rl * C57BL/6 * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ednrb^s-15DttMb mutation (0 available); any Ednrb mutation (103 available)
Mycbp2^tm1.1Adia mutation (0 available); any Mycbp2 mutation (223 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal nervous system morphology ( J:125702 )

• authors state that mice exhibit the same gross morphological defects as observed in Phr1^tm1.1Adia homozygotes

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