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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
lgStn
lid gap Stein
MGI:1857109
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
lgStn/lgStn Not Specified MGI:5320578


Genotype
MGI:5320578
hm1
Allelic
Composition
lgStn/lgStn
Genetic
Background
Not Specified
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phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
• corneal disorganization observed in histologicval sections of newborn
• Background Sensitivity: one or both eyes (J:5166)
• in overall severity, alleles rank in the order lg > lgStn = lgSt > lgGa > lgMl (J:7160)
• administration of cortisone to the mother on E14 of pregnancy normalizes eye development in offspring (J:7495)
• thyroxine administered to the mother at E10-E11 of gestation normalizes eye development in offspring (J:8009)
• detectable at E14-16, extensive at E17
• Background Sensitivity: one or both eyes are open at birth, with a 70-100 percent incidence of at least one eye affected depending on genetic background
• detected in histological analysis of 2 day old pups





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory