behavior/neurological
|
• after exertion, mice crouch in a corner of the cage and start trembling
• tremors were reduced by high doses of orphenadrine and hyoscine, but not alpha-methyldopa, atropine, barbituates, or nethalide
|
abnormal gait
(
J:5169
)
|
• lurching gait in which the hindlegs are lifted too high off the ground
|
growth/size/body
|
• lighter in weight than wild-type littermates throughout life
|
nervous system
| N |
• normal brain morphology
• normal levels of brain amines and acetylcholine
|


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