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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
sc
screw-tail
MGI:1857028
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
sc/sc involves: BALB MGI:5284832


Genotype
MGI:5284832
hm1
Allelic
Composition
sc/sc
Genetic
Background
involves: BALB
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
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phenotype observed in females
phenotype observed in males
N normal phenotype
skeleton
• anomalies likely result from retarded growth of the mandibular condyle, maxillary sutures, and connective tissue of the dental pulp
• the sternum is short, broad, unsegmented
• abnormalities of the sternum appear to result from retarded growth of the ribs which fails to bring the bilateral sternal bands into close association during development
• one more than normal
• results in sharp kinks in the thoracic or lumbar region

limbs/digits/tail
• the tail is tightly coiled at birth but "opens" as the mouse ages leaving the tail bent into various angles
• compared to other areas of the tail, the tail is thickened where angles occur

mortality/aging
• 24 per cent of mutant mice are dead at birth and more die by weaning but a few survive into adulthood

growth/size/body
• anomalies likely result from retarded growth of the mandibular condyle, maxillary sutures, and connective tissue of the dental pulp
• noticeable at birth

reproductive system
• few among the mutants that survive as adults breed

craniofacial
• anomalies likely result from retarded growth of the mandibular condyle, maxillary sutures, and connective tissue of the dental pulp





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory