Phenotypes associated with this allele

• Allele Symbol: pk
• Allele Name: plucked
• Allele ID: MGI:1856993
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	pk/pk	B6.D2-pk/J	MGI:3586895

Genotype
MGI:3586895

hm1

• Allelic Composition: pk/pk
• Genetic Background: B6.D2-pk/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

endocrine/exocrine glands

enlarged sebaceous gland ( J:15247 )

• glands continue to grow, rather than regress, during active hair growth and remain enlarged to the end of the hair cycle

integument

enlarged sebaceous gland ( J:15247 )

• glands continue to grow, rather than regress, during active hair growth and remain enlarged to the end of the hair cycle

abnormal coat appearance ( J:15247 )

• fur is missing or found in patches and is very short after all hair cycles

abnormal hair growth ( J:15247 )

• the first coat is delayed 6 days when short bristles appear on the head and a thick mat of bristles over the body

• distal ends of all hair types are missing

• Background Sensitivity: on other backgrounds scruffiness is replaced by short, irregular hairs

abnormal hair shaft morphology ( J:15247 )

• a medullated shaft does not form; keratinized material enfolds the hair tip at the level of the sebaceous gland

• abnormalities are due to disturbances to the external root sheath which breaks down prematurely as hair shaft begins to erupt

absent vibrissae ( J:15247 )

• on this background whiskers are entirely absent at birth

• Background Sensitivity: other backgrounds permit some growth

abnormal skin morphology ( J:15247 )

• thickening of epidermis and dermis are a response to failure of bent hair shafts to erupt normally

abnormal skin appearance ( J:15247 )

• at 6 days, when the coat normally comes in, the skin is shiny with fine, darkly pigmented wrinkles