Phenotypes associated with this allele

• Allele Symbol: cls
• Allele Name: coatloss
• Allele ID: MGI:1856823
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	cls/cls	involves: DBA/1Lac	MGI:2663402

Genotype
MGI:2663402

hm1

• Allelic Composition: cls/cls
• Genetic Background: involves: DBA/1Lac

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

lethality at weaning, incomplete penetrance ( J:15088 )

• many mutant animals die just before or after weaning

premature death ( J:15088 )

• a small number of mutant mice survive for some time after weaning

growth/size/body

decreased body size ( J:15088 )

• by three weeks of age, mutants are usually smaller than normal littermates

immune system

immune system phenotype ( J:15088 )

N • post-mortem, mutant mice exhibit apparently normal thymuses

integument

abnormal coat appearance ( J:15088 )

• an abnormal coat with a thin, greasy appearance is observed by 7-8 days of age

abnormal hair growth ( J:15088 )

focal hair loss ( J:15088 )

• by 3 weeks of age, only small ventral patches of hair are observed

hairless ( J:15088 )

• by 3 weeks of age, the coat is lost except for small ventral patches of hair

• mutants that survive post weaning may suddenly develop nearly full coats; however, these coats are typically lost within 1-2 weeks

sparse hair ( J:15088 )

• a thin coat is observed by 7-8 days of age

greasy coat ( J:15088 )

• a greasy coat is observed by 7-8 days of age

abnormal vibrissa number ( J:15088 )

• mutants are readily recognizable at birth by the reduced number of vibrissae