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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		clf2
cleft lip 2
MGI:1856822
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		clf2/clf2 AEJ.A/Jur MGI:2663303
cx2
 		Wnt9bclf1/Wnt9bclf1
clf2/clf2 		AEJ.A/Jur MGI:2663306
cx3
 		Wnt9bclf1/Wnt9bclf1
clf2/clf2+ 		AEJ.A/Jur MGI:3497750


Genotype
MGI:2663303
hm1
Allelic
Composition		 clf2/clf2
Genetic
Background		 AEJ.A/Jur
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
craniofacial
cleft upper lip ( J:69826 , J:92341 , J:25484 )
• increased risk of cleft lip and palate (J:69826)
• increased incidence of cleft lip and palate (J:92341)
cleft palate ( J:69826 , J:92341 )
• increased risk of cleft lip and palate (J:69826)

digestive/alimentary system
cleft palate ( J:69826 , J:92341 )
• increased risk of cleft lip and palate (J:69826)

growth/size/body
cleft upper lip ( J:69826 , J:92341 , J:25484 )
• increased risk of cleft lip and palate (J:69826)
• increased incidence of cleft lip and palate (J:92341)
cleft palate ( J:69826 , J:92341 )
• increased risk of cleft lip and palate (J:69826)




Genotype
MGI:2663306
cx2
Allelic
Composition		 Wnt9bclf1/Wnt9bclf1
clf2/clf2
Genetic
Background		 AEJ.A/Jur
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
clf2 mutation (0 available); any clf2 mutation (0 available)
Wnt9bclf1 mutation (4 available); any Wnt9b mutation (21 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
craniofacial
cleft upper lip ( J:69826 , J:92341 , J:25484 )
• increased risk of cleft lip and palate (J:69826)
• increased incidence of cleft lip and palate (J:92341)

growth/size/body
cleft upper lip ( J:69826 , J:92341 , J:25484 )
• increased risk of cleft lip and palate (J:69826)
• increased incidence of cleft lip and palate (J:92341)




Genotype
MGI:3497750
cx3
Allelic
Composition		 Wnt9bclf1/Wnt9bclf1
clf2/clf2+
Genetic
Background		 AEJ.A/Jur
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
clf2 mutation (0 available); any clf2 mutation (0 available)
Wnt9bclf1 mutation (4 available); any Wnt9b mutation (21 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
craniofacial
cleft upper lip ( J:69826 , J:92341 )
• increased risk of cleft lip and palate (J:69826)
• increased incidence of cleft lip and palate (J:92341)

growth/size/body
cleft upper lip ( J:69826 , J:92341 )
• increased risk of cleft lip and palate (J:69826)
• increased incidence of cleft lip and palate (J:92341)




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory