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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
cac
recessive cataract
MGI:1856813
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
cac/cac STOCK AxinFu-ki MGI:2658892


Genotype
MGI:2658892
hm1
Allelic
Composition
cac/cac
Genetic
Background
STOCK AxinFu-ki
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
cac mutation (3 available); any cac mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
• at one month of age there are degenerative changes in the posterior lens capsule and subcapsular tissue
• differences found between mutant and wild-type for alpha-,beta-and gamma-crystallins (J:268)
• another study was unable to demonstrate differences in relative amounts of lens proteins between mutants and normal mice of the same background (J:5031)
• animals develop cataracts by 1 month of age





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory