Phenotypes associated with this allele

• Allele Symbol: Agtpbp1^pcd-2J
• Allele Name: Purkinje cell degeneration 2 Jackson
• Allele ID: MGI:1856536
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Agtpbp1^pcd-2J/Agtpbp1^pcd-2J	involves: SM/J	MGI:4458342

Genotype
MGI:4458342

hm1

• Allelic Composition: Agtpbp1^pcd-2J/Agtpbp1^pcd-2J
• Genetic Background: involves: SM/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal motor coordination/balance ( J:74929 )

• mice homozygous for this allele display locomotor deficits much less severe than seen in mice homozygous for Agtpbp1^pcd-1J

ataxia ( J:74929 )

• mice homozygous for this allele develop ataxia later and is much less severe than seen in mice homozygous for Agtpbp1^pcd-1J

nervous system

nervous system phenotype ( J:74929 )

N • thalamic neurons show no abnormalities even after a year; these neurons degenerate in mice homozygous for other Agtpbp1 alleles

reproductive system

reduced male fertility ( J:74929 )

♂ • this allele has milder affects on fertility; mice homozygous for many other alleles show complete male infertility