Phenotypes associated with this allele

• Allele Symbol: Mitf^mi-ce
• Allele Name: cloudy-eye
• Allele ID: MGI:1856532
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mitf^mi-ce/Mitf^mi-ce	involves: DBA/2N	MGI:3525852

Genotype
MGI:3525852

hm1

• Allelic Composition: Mitf^mi-ce/Mitf^mi-ce
• Genetic Background: involves: DBA/2N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

pigmentation

abnormal eye pigmentation ( J:34879 )

• eyes are pale (cloudy white)

decreased eye pigmentation ( J:34879 )

• mice are white due to absence of pigment cells

hearing/vestibular/ear

abnormal inner ear morphology ( J:34879 )

abnormal cochlear hair cell morphology ( J:34879 )

• hair cells not fully developed

thin stria vascularis ( J:34879 )

• abnormally thin or absent

reproductive system

abnormal estrous cycle ( J:34879 )

♀ • average appearance of mating plug for paired matings is 13 days compared to 2 days for normal mice

abnormal fertility/fecundity ( J:34879 )

• females are unable to maintain a pregnancy when mated to a homozygous male: fetuses die between E16 and E18

vision/eye

abnormal eye pigmentation ( J:34879 )

• eyes are pale (cloudy white)

decreased eye pigmentation ( J:34879 )

• mice are white due to absence of pigment cells

abnormal lens morphology ( J:34879 )

cataract ( J:34879 )

• occasional cases of cataracts

abnormal eye development ( J:34879 )

microphthalmia ( J:34879 )

• asymmetrical eye opening (palpebral fissure) significantly smaller at all ages

• eyes decrease in volume with age

nervous system

abnormal cochlear hair cell morphology ( J:34879 )

• hair cells not fully developed