Phenotypes associated with this allele
Allelic Composition |
KitW-Jic/Kit+
|
|
Genetic Background |
involves: C57BL/6 |
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitW-Jic mutation
(0 available);
any
Kit mutation
(179 available)
|
|
|
immune system
|
• mice exhibit fewer mast cells in the skin than wild-type mice
|
hematopoietic system
|
• mice exhibit fewer mast cells in the skin than wild-type mice
|
pigmentation
integument
Allelic Composition |
KitW-Jic/KitW
|
|
Genetic Background |
involves: C57BL/6 * WB |
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitW mutation
(10 available);
any
Kit mutation
(179 available)
KitW-Jic mutation
(0 available);
any
Kit mutation
(179 available)
|
|
|
immune system
|
• mice exhibit no mast cells in the skin
|
|
• mast cells do not survive co-culture with fibroblast cells and exhibit impaired attachment
|
hematopoietic system
|
• mice exhibit no mast cells in the skin
|
|
• mast cells do not survive co-culture with fibroblast cells and exhibit impaired attachment
|
pigmentation
|
• mice are black-eyed with white coats
|
integument
|
• mice are black-eyed with white coats
|