Phenotypes associated with this allele

• Allele Symbol: Lmx1a^dr-sst
• Allele Name: shaker short tail
• Allele ID: MGI:1856495
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lmx1a^dr-sst/Lmx1a^dr-sst	involves: BALB/cCf * C57BL/6J * DBA/2J	MGI:3838353

Genotype
MGI:3838353

hm1

• Allelic Composition: Lmx1a^dr-sst/Lmx1a^dr-sst
• Genetic Background: involves: BALB/cCf * C57BL/6J * DBA/2J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

mortality/aging ( J:12032 )

N

premature death ( J:12032 )

• most mutants die by 30 days of age

behavior/neurological

abnormal motor coordination/balance ( J:12032 )

• mice often sit with widely splayed hindlegs and usually fall over when trying to groom or eat

impaired righting response ( J:12032 )

• as early as 10 days of age, mutant mice are unable to right themselves

abnormal resting posture ( J:12032 )

• while eating or grooming mice sit with widely splayed legs to gain balance

hyperactivity ( J:12032 )

hearing/vestibular/ear

deafness ( J:12032 )

nervous system

abnormal cerebellum development ( J:12032 )

• cerebellum is smaller than normal

abnormal cerebellar foliation ( J:12032 )

limbs/digits/tail

abnormal tail development ( J:12032 )

• tail is short, blunt and often has a small filament at the tip

short tail ( J:12032 )

• tail is blunt and often has a small filament at the tip

pigmentation

white spotting ( J:12032 )

• Background Sensitivity: presence depends on genetic background

integument

white spotting ( J:12032 )

• Background Sensitivity: presence depends on genetic background

bleb ( J:12032 )

• there may be a small blood bleb on the head