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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		CrygaTol
total opacity with lens vacuoles
MGI:1856493
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		CrygaTol/CrygaTol involves: 102/El * C3H * T STOCK MGI:3579817
ht2
 		CrygaTol/Cryga+ involves: 101 * C3H MGI:2175735
ht3
 		CrygaTol/Cryga+ involves: 102/El * C3H * T STOCK MGI:3579818


Genotype
MGI:3579817
hm1
Allelic
Composition		 CrygaTol/CrygaTol
Genetic
Background		 involves: 102/El * C3H * T STOCK
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
CrygaTol mutation (0 available); any Cryga mutation (16 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
ruptured lens capsule ( J:90087 )
• rupture of the posterior lens capsule is seen at 3 weeks of age
lens vacuoles ( J:90087 )
• high numbers of large vacuoles are seen in the remaining lens; however the retinas, iris, and cornea are normal
abnormal lens fiber morphology ( J:90087 )
• fiber cell nuclei are not fully degraded
nuclear cataract ( J:90087 )
• dense nuclear opacity is seen




Genotype
MGI:2175735
ht2
Allelic
Composition		 CrygaTol/Cryga+
Genetic
Background		 involves: 101 * C3H
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
CrygaTol mutation (0 available); any Cryga mutation (16 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
lens vacuoles ( J:23988 )
• lens vacuolization
total cataract ( J:23988 )
• total opacity




Genotype
MGI:3579818
ht3
Allelic
Composition		 CrygaTol/Cryga+
Genetic
Background		 involves: 102/El * C3H * T STOCK
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
CrygaTol mutation (0 available); any Cryga mutation (16 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
ruptured lens capsule ( J:90087 )
• rupture of the posterior lens capsule is seen at 3 weeks of age
lens vacuoles ( J:90087 )
• high numbers of large vacuoles are seen in the remaining lens; however the retinas, iris, and cornea are normal
abnormal lens fiber morphology ( J:90087 )
• fiber cell nuclei are not fully degraded
nuclear cataract ( J:90087 )
• dense nuclear opacity is seen




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory