Phenotypes associated with this allele

• Allele Symbol: Reln^rl-tg
• Allele Name: reeler tg
• Allele ID: MGI:1856417
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Reln^rl-tg/Reln^rl-tg	involves: C3H * C57BL/6 * DBA/2	MGI:3823084

Genotype
MGI:3823084

hm1

• Allelic Composition: Reln^rl-tg/Reln^rl-tg
• Genetic Background: involves: C3H * C57BL/6 * DBA/2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

tremors ( J:21534 )

• starting at 12 days after birth, tremors are observed

ataxia ( J:21534 )

abnormal posture ( J:21534 )

• starting at 12 days after birth, mice exhibit dystonic posture

abnormal gait ( J:21534 )

• starting at 12 days after birth, mice have an ataxic gait

nervous system

abnormal hippocampus granule cell layer ( J:21534 )

• cells are loosely packed and appear to merge with a region inferior to the dentate gyrus

abnormal hippocampus pyramidal cell layer ( J:21534 )

• neurons do not coalesce into distinct lamina and are arranged into 2 loosely organized bands

abnormal cerebellar cortex morphology ( J:21534 )

• cortex is shrunken and has inverted architecture where outer nuclear layer lies superficial to molecular and Purkinje cell layers

absent cerebellar foliation ( J:21534 )

• typical foliation is essentially absent

small cerebellum ( J:21534 )

• significantly reduced in size