All Phenotypes Atp7a<Mo-8J> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Atp7a^Mo-8J
mottled 8 Jackson
MGI:1856321

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Atp7a^Mo-8J/Atp7a⁺	involves: C3HeB/FeJ * C57BL/6J	MGI:4849928
ot2	Atp7a^Mo-8J/Y	involves: C3HeB/FeJ * C57BL/6J	MGI:4849927

Allelic Composition	Atp7a^Mo-8J/Atp7a⁺
Genetic Background	involves: C3HeB/FeJ * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atp7a^Mo-8J mutation (1 available); any Atp7a mutation (69 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

abnormal coat/hair pigmentation ( J:16313 )

diluted coat color ( J:16313 )

• mutant areas of the coat are diluted compared with normal pigmentation, appearing gray or white

irregular coat pigmentation ( J:16313 )

• due to X-inactivation

mosaic coat color ( J:16313 )

• the coat has areas of normal and diluted pigmentation depending on allele inactivation

behavior/neurological

hindlimb paralysis ( J:16313 )

• coincident in females with a significant proportion of coat being of mutant, diluted pigmentation

integument

abnormal coat/hair pigmentation ( J:16313 )

diluted coat color ( J:16313 )

• mutant areas of the coat are diluted compared with normal pigmentation, appearing gray or white

irregular coat pigmentation ( J:16313 )

• due to X-inactivation

mosaic coat color ( J:16313 )

• the coat has areas of normal and diluted pigmentation depending on allele inactivation

wavy vibrissae ( J:16313 )

Allelic Composition	Atp7a^Mo-8J/Y
Genetic Background	involves: C3HeB/FeJ * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atp7a^Mo-8J mutation (1 available); any Atp7a mutation (69 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

postnatal lethality ( J:38978 )

• affected males die 7-12 days after birth

behavior/neurological

hindlimb paralysis ( J:16313 )

pigmentation

abnormal coat/hair pigmentation ( J:16313 )

diluted coat color ( J:16313 )

• the coat is dirty white

integument

abnormal coat/hair pigmentation ( J:16313 )

diluted coat color ( J:16313 )

• the coat is dirty white

wavy vibrissae ( J:16313 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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