All Phenotypes Tyr<c-44H> MGI Mouse

Phenotypes associated with this allele

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tyr^c-44H/Tyr^c-44H	involves: 101/H * C3H/HeH	MGI:4836364
ht2	Tyr^c/Tyr^c-44H	involves: 101/H * C3H/HeH	MGI:4836392

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

abnormal coat/hair pigmentation ( J:12721 )

absent coat pigmentation ( J:12721 )

• the coat is white except for traces of pigmented hair in the ano-genital region, noted only in older mice

abnormal eye pigmentation ( J:12721 )

decreased eye pigmentation ( J:12721 )

• evident at birth allowing accurate classification of mice where Tyr^c and Tyr^c-44H are segregating

• at weaning homozygous mice have dark ruby eyes that intensify to nearly black by 3-4 months of age

vision/eye

abnormal eye pigmentation ( J:12721 )

decreased eye pigmentation ( J:12721 )

• evident at birth allowing accurate classification of mice where Tyr^c and Tyr^c-44H are segregating

• at weaning homozygous mice have dark ruby eyes that intensify to nearly black by 3-4 months of age

integument

abnormal coat/hair pigmentation ( J:12721 )

absent coat pigmentation ( J:12721 )

• the coat is white except for traces of pigmented hair in the ano-genital region, noted only in older mice

Allelic Composition	Tyr^c/Tyr^c-44H
Genetic Background	involves: 101/H * C3H/HeH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tyr^c mutation (79 available); any Tyr mutation (376 available)
Tyr^c-44H mutation (1 available); any Tyr mutation (376 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

absent coat pigmentation ( J:12721 )

• mice are white, albino as expected

abnormal eye pigmentation ( J:12721 )

• some, but not all mice, have eye color darker than typical of albino mice

vision/eye

abnormal eye pigmentation ( J:12721 )

• some, but not all mice, have eye color darker than typical of albino mice

integument

absent coat pigmentation ( J:12721 )

• mice are white, albino as expected

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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