Phenotypes associated with this allele

• Allele Symbol: Glrb^spa-Alb
• Allele Name: spastic Albany
• Allele ID: MGI:1856176
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Glrb^spa-Alb/Glrb^spa-Alb	C57BL/6Fla-H2-T18^a	MGI:3696838

Genotype
MGI:3696838

hm1

• Allelic Composition: Glrb^spa-Alb/Glrb^spa-Alb
• Genetic Background: C57BL/6Fla-H2-T18^a

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:64454 )

• die before weaning

muscle

muscle hypertonia ( J:64454 )

• progression to severe spasticity and rigidity with tremors

behavior/neurological

abnormal motor capabilities/coordination/movement ( J:64454 )

• behavioral abnormalities are improved by injections of aminooxyacetic acid, but this does not improve survival

impaired righting response ( J:64454 )

• early defect in righting reflex

tremors ( J:64454 )

• progression to severe spasticity and rigidity with tremors

abnormal gait ( J:64454 )

• stiffened gait