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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Krt27Re-wc
wavy coat
MGI:1856138
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Krt27Re-wc/Krt27Re-wc Not Specified MGI:3586821
ht2
Krt27Re-wc/Krt27+ Not Specified MGI:3586816


Genotype
MGI:3586821
hm1
Allelic
Composition
Krt27Re-wc/Krt27Re-wc
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Krt27Re-wc mutation (1 available); any Krt27 mutation (18 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
integument
• cycles of normal hair regrowth with partial dorsal loss begins between 18 and 26 days of age
• all hair types are affected (J:15247)
• waviness is seen two days earlier than in the heterozygote and is more pronounced (J:100076)
• the shaft of all hair types is irregular
• hair calibre and and septation of medulla varies continuously
• hair shafts twist and bend with parts showing swelling, flattening and longitudinal indentations
• both medulla and cortex have areas of dense pigmentation; where medullary structures break down, pigment aggregates on cortical ridges or is scattered
• whiskers are more curved and irregular than in heterozygote




Genotype
MGI:3586816
ht2
Allelic
Composition
Krt27Re-wc/Krt27+
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Krt27Re-wc mutation (1 available); any Krt27 mutation (18 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
integument
• about day 12, coat starts to grow in loose waves from shoulder region back
• a few days after birth whiskers are slightly bent, bending accentuated near tips





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory