Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cacna2d2du-td mutation
(0 available);
any
Cacna2d2 mutation
(72 available)
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behavior/neurological
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• while mice swim slowly, they are unable to hold onto a rope
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• mice exhibit slow movements
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• mice lie on their backs for minutes at a time, sometimes with the mouth and feet quivering
• when standing, one foot is often raised and quivers
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|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cacna2d2du-td mutation
(0 available);
any
Cacna2d2 mutation
(72 available)
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mortality/aging
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• mice exhibit high mortality rates between 3 and 4 weeks of age
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reproductive system
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• mice exhibit reduced reproductivity
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immune system
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• mice undergo thymus involution soon after the onset of neurological symptoms
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endocrine/exocrine glands
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• pituitary glands exhibit an increase in cellular population density compared to in wild-type pituitaries
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• mice undergo thymus involution soon after the onset of neurological symptoms
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growth/size/body
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• in female mice
(J:5596)
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hematopoietic system
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• mice undergo thymus involution soon after the onset of neurological symptoms
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nervous system
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• pituitary glands exhibit an increase in cellular population density compared to in wild-type pituitaries
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