Phenotypes associated with this allele

• Allele Symbol: Tbx15^de
• Allele Name: droopy ear
• Allele ID: MGI:1856014
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tbx15^de/Tbx15^de	STOCK J	MGI:3046103

Genotype
MGI:3046103

hm1

• Allelic Composition: Tbx15^de/Tbx15^de
• Genetic Background: STOCK J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, incomplete penetrance ( J:233 )

• 16% of mice die before weaning

pigmentation

irregular coat pigmentation ( J:233 )

• in combination with a^t and A^w lighter belly hair comes up farther on the sides and face than patterning of a^t or A^w

craniofacial

broad nasal bridge ( J:233 )

shortened head ( J:233 )

• elevated skull contributes to lowered ear position with pinnae projecting laterally

growth/size/body

broad nasal bridge ( J:233 )

shortened head ( J:233 )

• elevated skull contributes to lowered ear position with pinnae projecting laterally

abnormal postnatal growth ( J:233 )

• body size is reduced body size compared to normal siblings

limbs/digits/tail

abnormal limb bone morphology ( J:233 )

• disproportionate shortening of limb bones

skeleton

abnormal limb bone morphology ( J:233 )

• disproportionate shortening of limb bones

small acromion ( J:233 )

small scapula ( J:233 )

abnormal skeleton development ( J:233 )

• defects are first seen at E12 of development

• defects are due to abnormal cartilage formation and thin mesenchymal condensations

integument

irregular coat pigmentation ( J:233 )

• in combination with a^t and A^w lighter belly hair comes up farther on the sides and face than patterning of a^t or A^w

respiratory system

broad nasal bridge ( J:233 )