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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Crygenz
dominant cataract 2, nuclear and zonular opacity
MGI:1855995
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Crygenz/Crygenz involves: 101 * C3H MGI:2175812
ht2
 		Crygenz/Cryge+ involves: 101 * C3H MGI:3836290


Genotype
MGI:2175812
hm1
Allelic
Composition		 Crygenz/Crygenz
Genetic
Background		 involves: 101 * C3H
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Crygenz mutation (1 available); any Cryge mutation (23 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
cataract ( J:6686 )
• cataracts are bilateral and the opacity is more severe than found in the heterozygote
nuclear cataract ( J:6686 )
• dense opacity involves the whole lens but not including the peripheral layer




Genotype
MGI:3836290
ht2
Allelic
Composition		 Crygenz/Cryge+
Genetic
Background		 involves: 101 * C3H
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Crygenz mutation (1 available); any Cryge mutation (23 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
cataract ( J:6686 , J:9528 )
• bilateral (J:6686)
• central cataracts, with opacity of the nucleus and perinuclear zone (J:9528)
nuclear cataract ( J:6686 )
• the granular opacity of the nucleus is surrounded by concentric, less opaque perinuclear zones
• the perinuclear layer may liquify




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/07/2025
MGI 6.24 		The Jackson Laboratory