Cxcl15^{em1(icre)Tesp}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cxcl15^{em1(icre)Tesp}
• Name: C-X-C motif chemokine ligand 15; endonuclease-mediated mutation 1, Thomas E Spencer
• MGI ID: MGI:8476120
• Synonyms: Cxcl15^Cre
• Gene: Cxcl15 Location: Chr5:90942393-90950926 bp, + strand Genetic Position: Chr5, 44.78 cM
• Alliance: Cxcl15^{em1(icre)Tesp} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission:
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout, Recombinase)
• Mutation: Insertion
• Cxcl15^{em1(icre)Tesp} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Cxcl15 (MGI:1339941)

• Mutation details:

  CRISPR/Cas9 genome editing technology was used to insert a iCre recombinase coding sequence into the endogenous ATG start site of the gene. (J:394216)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Cxcl15 (mouse) Summary of all recombinase alleles driven by Cxcl15. Alliance mouse Cxcl15 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cxcl15 Mutation: 18 strains or lines available

References

• Original: J:394216 Kelleher AM, et al., A Cxcl15 Cre Recombinase Mouse Model Useful to Study Gland Development in the Uterus. Genesis. 2025 Oct;63(5):e70026
• All: 1 reference(s)