Sult2a8^tm1Sstl
Targeted Allele Detail

Summary

• Symbol: Sult2a8^tm1Sstl
• Name: sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 8; targeted mutation 1, Susanna Sau-Tuen Lee
• MGI ID: MGI:8448636
• Gene: Sult2a8 Location: Chr7:14144611-14180694 bp, - strand Genetic Position: Chr7, 8.2 cM
• Alliance: Sult2a8^tm1Sstl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:344979
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details:

  Exon 3 and parts of intron 2 and 3 were replaced with an FRT-flanked neomycin cassette and loxP site. (J:344979)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sult2a8 Mutation: 23 strains or lines available

References

• Original: J:344979 Wang, K, Functional and Structural Studies of Cytosolic Sulfotransferase (Sult2a8) in Bile Acid and Energy Metabolism. PhD Thesis - The Chinese University of Hong Kong. 2020
• All: 2 reference(s)