Npw^tm1Ywa
Targeted Allele Detail

Summary

• Symbol: Npw^tm1Ywa
• Name: neuropeptide W; targeted mutation 1, Masashi Yanagisawa
• MGI ID: MGI:8409912
• Gene: Npw Location: Chr17:24876304-24877431 bp, - strand Genetic Position: Chr17, 12.45 cM
• Alliance: Npw^tm1Ywa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:232185
• Parent Cell Line: SM1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details:

  Exon 1 was replaced with a nLacZ-FRT-neo-FRT cassette using proximal 8-kb and distal 1.2-kb flanking genomic sequences. In situ hybridization using a riboprobe specific for exon 1 showed no signal in homozygotes. (J:232185)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Npw Mutation: 9 strains or lines available

References

• Original: J:232185 Motoike T, et al., Mesolimbic neuropeptide W coordinates stress responses under novel environments. Proc Natl Acad Sci U S A. 2016 May 24;113(21):6023-8
• All: 1 reference(s)