Ankrd33b^tm1Tfur
Targeted Allele Detail

Summary

• Symbol: Ankrd33b^tm1Tfur
• Name: ankyrin repeat domain 33B; targeted mutation 1, Takahisa Furukawa
• MGI ID: MGI:8409343
• Synonyms: Panky-like^-
• Gene: Ankrd33b Location: Chr15:31291624-31367872 bp, - strand Genetic Position: Chr15, 12.76 cM, cytoband B3.2
• Alliance: Ankrd33b^tm1Tfur page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:390147
• Parent Cell Line: JM8A3 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details:

  A reversed loxP-PGKneo-loxP cassette replaced the exon 1 containing region. Western blot analysis confirmed absence of protein in homozygotes. (J:390147)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ankrd33b Mutation: 24 strains or lines available

References

• Original: J:390147 Tu HY, et al., Transcription co-repressors Panky and Panky-like modulate ganglioside levels and are essential for retinal cone photoreceptor structure and survival. J Neurosci. 2026 Jul 16;:e0052262026
• All: 1 reference(s)