Tpbpa^{em1(icre)Jilu}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tpbpa^{em1(icre)Jilu}
• Name: trophoblast specific protein alpha; endonuclease-mediated mutation 1, Jinhua Lu
• MGI ID: MGI:8403717
• Synonyms: Tpbpalpha-iCre-EGFP
• Gene: Tpbpa Location: Chr13:61086306-61089750 bp, - strand Genetic Position: Chr13, 32.57 cM
• Alliance: Tpbpa^{em1(icre)Jilu} page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase, Reporter)
• Mutation: Insertion
• Tpbpa^{em1(icre)Jilu} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Tpbpa (MGI:98795)

• Mutation details:

  CRISPR/cas-mediated targeting introduced the IRES, improved recombinase gene (icre), a PA2 sequence, and EGFP reporter gene. (J:377590)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Tpbpa (mouse) Summary of all recombinase alleles driven by Tpbpa. Comparative matrix view of recombinase activities Alliance mouse Tpbpa gene page

Expression

In Mice Carrying this Mutation:

56 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tpbpa Mutation: 7 strains or lines available

References

• Original: J:377590 Ban S, et al., Generation of Tpbpalpha-iCre-EGFP Knock-In Mice for Trophoblast Subtype-Specific Gene Manipulation. Genesis. 2025 Dec;63(6):e70034
• All: 1 reference(s)