Rps19bp1^em1.1Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rps19bp1^em1.1Gpt
• Name: ribosomal protein S19 binding protein 1; endonuclease-mediated mutation 1.1, GemPharmatech
• MGI ID: MGI:8401679
• Synonyms: Rps19bp1^gKO
• Gene: Rps19bp1 Location: Chr15:80144815-80148507 bp, - strand Genetic Position: Chr15, 37.85 cM
• Alliance: Rps19bp1^em1.1Gpt page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details:

  Endonuclease-mediated mutation generated using CRISPR/Cas9 introducing loxP sites flanking critical exon(s) to create a conditional allele. Cre-mediated recombination removed the floxed region. (J:379595)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rps19bp1 Mutation: 12 strains or lines available

References

• Original: J:379595 Zhang Z, et al., Transcriptional readthrough at Atf4 locus suppresses Rps19bp1 and impairs heart development. Cardiovasc Res. 2026 Feb 14;121(18):2909-2921
• All: 1 reference(s)