Cdkn2a^em1(dre)Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cdkn2a^em1(dre)Gpt
• Name: cyclin dependent kinase inhibitor 2A; endonuclease-mediated mutation 1, GemPharmatech
• MGI ID: MGI:8364613
• Synonyms: Cdkn2a(p16INK4a)^{em1Cin(LSL-P2A-Dre)}
• Gene: Cdkn2a Location: Chr4:89192710-89212856 bp, - strand Genetic Position: Chr4, 42.15 cM, cytoband C3-C6
• Alliance: Cdkn2a^em1(dre)Gpt page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, Recombinase)
• Mutation: Insertion
• Cdkn2a^em1(dre)Gpt expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Cdkn2a (MGI:104738)

• Mutation details:

  Endonuclease-mediated mutation generated using CRISPR/Cas9 resulting in targeted insertion of LSL-P2A-Dre at the endogenous locus. (J:293217)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Cdkn2a (mouse) Summary of all recombinase alleles driven by Cdkn2a. Alliance mouse Cdkn2a gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cdkn2a Mutation: 60 strains or lines available

References

• Original: J:293217 GemPharmatech, GemPharmatech Website. 2020
• All: 1 reference(s)