Tmco2^em1Osb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tmco2^em1Osb
• Name: transmembrane and coiled-coil domains 2; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:8347629
• Synonyms: Tmco2^-
• Gene: Tmco2 Location: Chr4:120962848-120966414 bp, - strand Genetic Position: Chr4, 56.8 cM
• Alliance: Tmco2^em1Osb page

Mutation origin

• Strain of Origin: (C57BL/6NJcl x DBA/2NJcl)F2

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas-mediated targeting deleted 3396 bp. (J:385300)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tmco2 Mutation: 10 strains or lines available

References

• Original: J:385300 Chang HY, et al., Mouse genome engineering uncovers 18 genes dispensable for male reproduction. Andrology. 2026 Mar;14(3):833-846
• All: 1 reference(s)