Gt(ROSA)26Sor^tm3Osb
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^tm3Osb
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 3, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:8347540
• Synonyms: ROSA26/Neo/mintbody
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^tm3Osb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:350437
• Parent Cell Line: EGR-G101 (ES Cell)
• Strain of Origin: C57BL/6NSlc-Tg(CAG-EGFP,Acr-EGFP)2Osb

Mutation description

• Allele Type: Targeted (Conditional ready, Epitope tag, Reporter)
• Mutation: Insertion
• Mutation details: The targeting construct introduced into the locus a conditional expressed mCherry reporter gene tagged with H4K20me1-mintbody following Flp-mediated recombination of an FRT-flanked stop cassette. (J:350437)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1212 strains or lines available

References

• Original: J:350437 Sato Y, et al., Visualizing histone H4K20me1 in knock-in mice expressing the mCherry-tagged modification-specific intracellular antibody. Histochem Cell Biol. 2024 Jul;162(1-2):41-52
• All: 1 reference(s)