Tg(Acta2-cre/ERT2)1Skom
Transgene Detail

Summary

• Symbol: Tg(Acta2-cre/ERT2)1Skom
• Name: transgene insertion 1, Shingo Komura
• MGI ID: MGI:8346923
• Synonyms: alphaSMA-CreERT2
• Transgene: Tg(Acta2-cre/ERT2)1Skom Location: unknown
• Alliance: Tg(Acta2-cre/ERT2)1Skom page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Acta2-cre/ERT2)1Skom expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Acta2 (MGI:87909)

• Mutation details: The mouse promoter from BAC clone RP23-370F21 drives inducible, smooth muscle cell-specified expression of the cre/ERT2 fusion gene. (J:368857)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Acta2 (mouse) Summary of all recombinase alleles driven by Acta2. Alliance mouse Acta2 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:368857 Goto A, et al., PI3K-Akt signalling regulates Scx-lineage tenocytes and Tppp3-lineage paratenon sheath cells in neonatal tendon regeneration. Nat Commun. 2025 Apr 20;16(1):3734
• All: 1 reference(s)