Fkbp9^tm1.2Xdz
Targeted Allele Detail

Summary

• Symbol: Fkbp9^tm1.2Xdz
• Name: FK506 binding protein 9; targeted mutation 1.2, Xu-Dong Zhao
• MGI ID: MGI:8326152
• Gene: Fkbp9 Location: Chr6:56809044-56856343 bp, + strand Genetic Position: Chr6, 27.74 cM
• Alliance: Fkbp9^tm1.2Xdz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:357743
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 2 and an FRT-flanked pGK-Neo cassette and second loxP site were inserted downstream of exon 2. The neomycin resistance cassette was removed via flp-mediated recombination. Cre-mediated recombination deleted exon 2. (J:357743)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fkbp9 Mutation: 20 strains or lines available

References

• Original: J:357743 Li S, et al., The stability of FKBP9 maintained by BiP is crucial for glioma progression. Genes Dis. 2024 Nov;11(6):101123
• All: 1 reference(s)