Spdye4a^em1Hzhe
Endonuclease-mediated Allele Detail

Summary

• Symbol: Spdye4a^em1Hzhe
• Name: speedy/RINGO cell cycle regulator family, member E4A; endonuclease-mediated mutation 1, Haoyu Zheng
• MGI ID: MGI:8317260
• Gene: Spdye4a Location: Chr5:143202071-143212645 bp, - strand Genetic Position: Chr5, 82.01 cM, cytoband G2
• Alliance: Spdye4a^em1Hzhe page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 technology generated a 5 bp deletion in exon 2 resulting in a frameshift mutation (c.323_327delCCCAG), Gln108SerfsTer10. This corresponds to c.325_329del, p.Gln109Serfs*11 on Genome Build GRCm39. (J:344875)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Spdye4a Mutation: 10 strains or lines available

References

• Original: J:344875 Xu H, et al., Murine fertility and spermatogenesis are independent of the testis-specific Spdye4a gene. Gen Comp Endocrinol. 2023 Jan 1;330:114148
• All: 1 reference(s)