Hoxa5^tm2.1Ljea
Targeted Allele Detail

Summary

• Symbol: Hoxa5^tm2.1Ljea
• Name: homeobox A5; targeted mutation 2.1, Lucie Jeannotte
• MGI ID: MGI:8293376
• Synonyms: Hoxa5^FLAG
• Gene: Hoxa5 Location: Chr6:52178768-52181437 bp, - strand Genetic Position: Chr6, 25.4 cM
• Alliance: Hoxa5^tm2.1Ljea page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:371531
• Parent Cell Line: KV1 (ES Cell)
• Strain of Origin: (C57BL/6J x 129S6/SvEvTac)F1

Mutation description

• Allele Type: Targeted (Epitope tag)
• Mutation: Insertion
• Mutation details: The targeting construct inserted a FLAG tag before the stop codon and floxed neomycin resistance cassette. Cre-mediated recombination removed the selection cassette. (J:371531)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hoxa5 Mutation: 30 strains or lines available

References

• Original: J:371531 Frenette B, et al., HOXA5-driven transcriptional program in lung development. Dev Biol. 2025 Aug 13;527:191-205
• All: 1 reference(s)