Stat3^{Tn(pb-Act-RFP)1.091222007-HRAZhu}
Transposon induced Allele Detail

Summary

• Symbol: Stat3^{Tn(pb-Act-RFP)1.091222007-HRAZhu}
• Name: signal transducer and activator of transcription 3; transposon insertion 1.091222007-HRA, Yuan Zhuang
• MGI ID: MGI:8292591
• Synonyms: 378174
• Gene: Stat3 Location: Chr11:100777632-100830447 bp, - strand Genetic Position: Chr11, 63.82 cM
• Alliance: Stat3^{Tn(pb-Act-RFP)1.091222007-HRAZhu} page

Mutation origin

• Strain of Origin: FVB/NJ

Mutation description

• Allele Type: Transposon induced (Null/knockout)
• Mutation: Transposon insertion
• Mutation details: The transposon containing an unspecified hybrid actin promoter driving expression of red fluorescent protein (RFP) flanked by piggyBac-specific left and right terminal sequences was co-injected with a piggyBac-containing transgene to mobilize the transposon. This line contains a transposon inserted into Stat3 at position 100774559 (Ensembl release 64). (J:378174)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Stat3 Mutation: 72 strains or lines available

References

• Original: J:378174 Yan B, et al., Embryonic Lethal Phenotyping to Identify Candidate Genes Related with Birth Defects. Int J Mol Sci. 2024 Aug 13;25(16)
• All: 1 reference(s)