Nf1^{Tn(pb-Act-RFP)1.W39-10Zhu}
Transposon induced Allele Detail

Summary

• Symbol: Nf1^{Tn(pb-Act-RFP)1.W39-10Zhu}
• Name: neurofibromin 1; transposon insertion 1.W39-10, Yuan Zhuang
• MGI ID: MGI:8292585
• Synonyms: Nf1^PB
• Gene: Nf1 Location: Chr11:79230519-79472438 bp, + strand Genetic Position: Chr11, 46.74 cM, cytoband B4-5
• Alliance: Nf1^{Tn(pb-Act-RFP)1.W39-10Zhu} page

Mutation origin

• Strain of Origin: FVB/NJ

Mutation description

• Allele Type: Transposon induced (Null/knockout)
• Mutation: Transposon insertion
• Mutation details: The transposon containing an unspecified hybrid actin promoter driving expression of red fluorescent protein (RFP) flanked by piggyBac-specific left and right terminal sequences was co-injected with a piggyBac-containing transgene to mobilize the transposon. This line contains a transposon inserted into Nf1 at position 79250223 (Ensembl release 64). (J:378174)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nf1 Mutation: 158 strains or lines available

References

• Original: J:378174 Yan B, et al., Embryonic Lethal Phenotyping to Identify Candidate Genes Related with Birth Defects. Int J Mol Sci. 2024 Aug 13;25(16)
• All: 1 reference(s)