Rxfp1^em2(flp)Zell
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rxfp1^em2(flp)Zell
• Name: relaxin/insulin-like family peptide receptor 1; endonuclease-mediated mutation 2, Lori M Zeltser
• MGI ID: MGI:8290823
• Synonyms: Rxfp1-flp, Rxfp1^tm1(flp)Zel
• Gene: Rxfp1 Location: Chr3:79548918-79645187 bp, - strand Genetic Position: Chr3, 34.94 cM
• Alliance: Rxfp1^em2(flp)Zell page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• Rxfp1^em2(flp)Zell expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Rxfp1 (MGI:2682211)

• A P2A-flp construct was inserted in-frame via CRISPR/cas9 mediated recombination. (J:379849)
• Inheritance: Not Specified

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Rxfp1 (mouse) Summary of all recombinase alleles driven by Rxfp1. Alliance mouse Rxfp1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rxfp1 Mutation: 56 strains or lines available

References

• Original: J:379849 Neri D, et al., Distinct sympathetic projections to brown fat regulate thermogenesis and glucose tolerance. Nat Metab. 2026 Jan 20
• All: 1 reference(s)