Slc18a1^em1(cre)Zell
Endonuclease-mediated Allele Detail

Summary

• Symbol: Slc18a1^em1(cre)Zell
• Name: solute carrier family 18 (vesicular monoamine), member 1; endonuclease-mediated mutation 1, Lori M Zeltser
• MGI ID: MGI:8290822
• Synonyms: Slc18a1-cre, Slc18a1^tm1(cre)Zel
• Gene: Slc18a1 Location: Chr8:69490363-69541887 bp, - strand Genetic Position: Chr8, 33.88 cM
• Alliance: Slc18a1^em1(cre)Zell page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• Slc18a1^em1(cre)Zell expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Slc18a1 (MGI:106684)

• A P2A-nlscre construct was inserted in-frame via CRISPR/cas9 mediated recombination. (J:379849)
• Inheritance: Not Specified

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Slc18a1 (mouse) Summary of all recombinase alleles driven by Slc18a1. Alliance mouse Slc18a1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc18a1 Mutation: 22 strains or lines available

References

• Original: J:379849 Neri D, et al., Distinct sympathetic projections to brown fat regulate thermogenesis and glucose tolerance. Nat Metab. 2026 Jan 20
• All: 1 reference(s)