Del(10Ddt-Gstt2)2Bhk
Targeted Allele Detail

Summary

• Symbol: Del(10Ddt-Gstt2)2Bhk
• Name: deletion, Chr 10, Beverly H Koller 2
• MGI ID: MGI:8288654
• Gene: Del(10Ddt-Gstt2)2Bhk Location: unknown Genetic Position: Chr10, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:286217
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intergenic deletion
• Del(10Ddt-Gstt2)2Bhk involves 7 genes/genome features (Ddt, Gm20441, Gstt3 ...) View all
• The targeting construct replaced 65 kb with a neomycin resistance cassette. (J:286217)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(10Ddt-Gstt2)2Bhk Mutation: 0 strains or lines available

References

• Original: J:286217 Xiang Z, et al., Mice lacking three Loci encoding 14 glutathione transferase genes: a novel tool for assigning function to the GSTP, GSTM, and GSTT families. Drug Metab Dispos. 2014 Jun;42(6):1074-83
• All: 2 reference(s)