Cdk2^em2Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cdk2^em2Cya
• Name: cyclin dependent kinase 2; endonuclease-mediated mutation 2, Cyagen Biosciences
• MGI ID: MGI:8286464
• Synonyms: Cdk2^em1flox
• Gene: Cdk2 Location: Chr10:128533808-128540900 bp, - strand Genetic Position: Chr10, 77.13 cM, cytoband D3
• Alliance: Cdk2^em2Cya page

Mutation origin

• Strain of Origin: C57BL/6JCya

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Exons 2-3 were flanked by loxP sites. (J:333861)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cdk2 Mutation: 16 strains or lines available

References

• Original: J:333861 Qin J, et al., Bud31-mediated alternative splicing is required for spermatogonial stem cell self-renewal and differentiation. Cell Death Differ. 2023 Jan;30(1):184-194
• All: 1 reference(s)