Tbx2^em1(IMPC)Bay
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tbx2^em1(IMPC)Bay
• Name: T-box 2; endonuclease-mediated mutation 1, Baylor College of Medicine
• MGI ID: MGI:8283363
• Gene: Tbx2 Location: Chr11:85723441-85732774 bp, + strand Genetic Position: Chr11, 51.34 cM
• Alliance: Tbx2^em1(IMPC)Bay page
• IMPC: Tbx2 gene page

Mutation origin

• Strain of Origin: C57BL/6N
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at Baylor College of Medicine using Cas9 and guides with spacer sequences GATTCCCTCACCATAGGGTA and GCGGGATGCTAGTCCCACTA that targeted exon(s) ENSMUSE00000105666.2. This resulted in deletion(s) of 4 bp (location: Chr11:85724758-85724761; GRCm39), 1345 bp (location: Chr11:85724766-85726110; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tbx2 Mutation: 31 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 2 reference(s)