Spidr^em1Jzc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Spidr^em1Jzc
• Name: scaffolding protein involved in DNA repair; endonuclease-mediated mutation 1, Zi-Jiang Chen
• MGI ID: MGI:8283309
• Gene: Spidr Location: Chr16:15707088-15964715 bp, - strand Genetic Position: Chr16, 10.09 cM
• Alliance: Spidr^em1Jzc page

Mutation origin

• Strain of Origin: (C57BL/6 x DBA/2)F2

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology deleted exons 2-3. (J:335565)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Spidr Mutation: 93 strains or lines available

References

• Original: J:335565 Huang T, et al., SPIDR is required for homologous recombination during mammalian meiosis. Nucleic Acids Res. 2023 May 8;51(8):3855-3868
• All: 1 reference(s)