Lrrc56^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Lrrc56^em1Cya
• Name: leucine rich repeat containing 56; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:8276963
• Gene: Lrrc56 Location: Chr7:140774070-140789968 bp, + strand Genetic Position: Chr7, 86.48 cM
• Alliance: Lrrc56^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6JCya

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology deleted exons 4 to 12. (J:377011)

Disease models

Expression

In Structures Affected by this Mutation:

8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lrrc56 Mutation: 21 strains or lines available

References

• Original: J:377011 Xie XH, et al., LRRC56 deficiency cause motile ciliopathies in humans and mice. Front Genet. 2025;16:1658063
• All: 1 reference(s)